oreon

Products

Filler - AESSOA

SAFETY

Purified product yields minimize side effects by eliminating uncreated materials. Performed ideal washing process to achieve greater safety of the product. Specialized washing process allows consistent product properties (Osmotic pressure, PH) BDDE residual and Endotoxin levels are near zero, below detection limit, increasing patient safety.

Preclinical Test Result
Category	Standard	Result
Appearance	Transparent and colorless viscous liquid with no foreign substances	Satisfied
pH	6.8 ~ 7.5	6.83
BDDE Residue	Maximum 2.0ppm	0 ppm
Heavy Metal	Maximum 10.0ppm	Below 10ppm
Injection Force	Maximum 30N	14.9
Osmotic Pressure	200 ~ 400 mmol/kg	318mmol/kg
Volume	Minimum 1.0mL	1.07~1.09mL
Aseptic / Toxic	Aseptic / Toxic	Satisfied
Endotoxin	Below 12.5 EU/mL	Below 0.02 EU/mL

EFFECTIVENESS

AESSOA is applied with a special technology called Dap Dancing Technology to increase elasticity through physical crosslinking This technology helps to prolong the longevity of HA.

Viscoelasticity

High viscoelasticity allows to maintain good volume for a long duration

Frequency Sweep Test

Test Condition
Analysis Equipment	KINEXUX Pro+ Model : KNX2212 Serial No : MAL1183889
Target temperature	25℃
Start frequency	0.1 Hz
End frequency	10 Hz
Shear strain	1.0%
Samples per decade	10

Frequency Sweep Test result

Dap Dancing Technology

Increases elasticity through physical crosslinking, Prolong the longevity of HA

High-Density Dapping Process

= specialized manufacturing process

Increase of Viscoelasticity

Analysis Result
Vibrate	Viscosity at 0.1Hz	Viscosity Change(%)
Before Vibration (Initial)	189.9 Pa	-
After Vibration (10mins)	193.5 Pa	1.89
After Vibration (20mins)	207.0 Pa	-

CONVENIENCE EXTRUSION FORCE

AESSOA has a consistent injection force which allows uniform and smooth injection, reduceing tissue damage and improving the safety of the procedures.

Convenience Extrusion Force

Consistent extrusion force allows smooth injection, therefore, increased convenience

Extrusion Force